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Compensatory enlargement of the liver after treatment of hepatocellular carcinoma with carbon ion radiotherapy-Relation to prognosis and liver function
https://repo.qst.go.jp/records/45963
https://repo.qst.go.jp/records/459638903fde6-e25d-40c6-909d-405ec24770ed
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-12-13 | |||||
| タイトル | ||||||
| タイトル | Compensatory enlargement of the liver after treatment of hepatocellular carcinoma with carbon ion radiotherapy-Relation to prognosis and liver function | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Imada, Hiroshi
× Imada, Hiroshi× Katou, Hirotoshi× Yasuda, Shigeo× Yamada, Shigeru× Yanagi, Takeshi× Hara, Ryusuke× Kishimoto, Riwa× Kandatsu, Susumu× Minohara, Shinichi× Mizoe, Junetsu× Kamada, Tadashi× Yokosuka, Osamu× Tsujii, Hirohiko× 今田 浩史× 加藤 博敏× 安田 茂雄× 山田 滋× 柳 剛× 原 竜介× 岸本 理和× 神立 進× 蓑原 伸一× 溝江 純悦× 鎌田 正× 横須賀 収× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | BACKGROUND AND PURPOSE: To examine whether liver volume changes affect prognosis and hepatic function in patients treated with carbon ion radiotherapy (CIRT) for hepatocellular carcinoma (HCC). MATERIAL AND METHODS: Between April 1995 and March 2003, among the cases treated with CIRT, 43 patients with HCC limited to the right hepatic lobe were considered eligible for the study. The left lateral segment was defined as the non-irradiated region. Liver volume was measured using contrast CT at 0, 3, 6, and 12 months after CIRT. We examined serum albumin, prothrombin activity, and total bilirubin level as hepatic functional reserve. RESULTS: After CIRT, the non-irradiated region showed significant enlargement, and enlarged volume of this region 3 months after CIRT 50 cm(3) was a prognostic factor. The 5-year overall survival rates were 48.9% in the larger enlargement group (enlarged volume of non-irradiated region 3 months after CIRT > or =50 cm(3)) and 29.4% in the smaller enlargement group (as above, <50 cm(3)). The larger enlargement group showed better hepatic functional reserve than the smaller enlargement group 12 months after CIRT. CONCLUSIONS: This study suggests that compensatory enlargement in the non-irradiated liver after CIRT contributes to the improvement of prognosis. |
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| 書誌情報 |
Radiotherapy and Oncology 巻 96, 号 2, p. 236-242, 発行日 2010-08 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0167-8140 | |||||
