WEKO3
アイテム
{"_buckets": {"deposit": "7c5e0ae7-2a66-4cfb-91aa-2c04abda8a62"}, "_deposit": {"created_by": 1, "id": "44680", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "44680"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00044680", "sets": ["1"]}, "author_link": ["443664", "443663"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "333", "bibliographicPageStart": "329", "bibliographicVolumeNumber": "1", "bibliographic_titles": [{"bibliographic_title": "International Journal of Low Radiation"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Non-tumour-inducing doses exist in dose-response data on experimental animals and humans, although a linear non-threshold model has been adopted for estimating cancer risk of ionising radiation at a low dose region for radiation protection purposes. Here, data on non- tumour dose, Dnt, the maximum dose at which a statistically significant increase of tumours is not observed, were reviewed in the literature. Dnt values range from 0.1 to 3 Gy for a variety of tumours induced by acute whole-body irradiation at low LET. This becomes one order higher by fractionation of radiation dose and further by extending irradiation chronically. Non-tumour doses for irradiation of a part of the body are one order higher than those for whole-body irradiation, indicating a higher tolerance level in the partial-body irradiation. Tumour data with high LET radiation also show non-tumour dose and its decrease at a very low dose rate. The variation of Dnt is explained by the host tolerance, including inducible and non-inducible DNA repair, apoptotic elimination of unrepaired cells, and immunological suppression of tumour development.", "subitem_description_type": "Abstract"}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1477-6545", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tanooka, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "443663", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "田ノ岡 宏", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "443664", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/44680", "pubdate": {"attribute_name": "公開日", "attribute_value": "2006-10-20"}, "publish_date": "2006-10-20", "publish_status": "0", "recid": "44680", "relation": {}, "relation_version_is_last": true, "title": ["Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses"], "weko_shared_id": -1}
Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses
https://repo.qst.go.jp/records/44680
https://repo.qst.go.jp/records/446809ba3f72a-f019-4940-9623-4cc10bc17ed3
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2006-10-20 | |||||
タイトル | ||||||
タイトル | Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Tanooka, Hiroshi
× Tanooka, Hiroshi× 田ノ岡 宏 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Non-tumour-inducing doses exist in dose-response data on experimental animals and humans, although a linear non-threshold model has been adopted for estimating cancer risk of ionising radiation at a low dose region for radiation protection purposes. Here, data on non- tumour dose, Dnt, the maximum dose at which a statistically significant increase of tumours is not observed, were reviewed in the literature. Dnt values range from 0.1 to 3 Gy for a variety of tumours induced by acute whole-body irradiation at low LET. This becomes one order higher by fractionation of radiation dose and further by extending irradiation chronically. Non-tumour doses for irradiation of a part of the body are one order higher than those for whole-body irradiation, indicating a higher tolerance level in the partial-body irradiation. Tumour data with high LET radiation also show non-tumour dose and its decrease at a very low dose rate. The variation of Dnt is explained by the host tolerance, including inducible and non-inducible DNA repair, apoptotic elimination of unrepaired cells, and immunological suppression of tumour development. | |||||
書誌情報 |
International Journal of Low Radiation 巻 1, 号 3, p. 329-333, 発行日 2004 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1477-6545 |