量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果(学会誌発表論文、学会発表、研究開発報告書、特許等)を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
Thank you very much for using our website. On the 11th of March 2019, this site was moved from our own network server to the JAIRO Cloud network server. If you previously bookmarked this site, that bookmark will no longer work. We would be grateful if you could bookmark the website again. Thank you very much for your understanding and cooperation.
Physiologically decreased F-18 fluorodeoxyglucose uptake in the lower vertebrae associated with daily drinking habit in Japanese men with alcohol flushing reaction.
利用統計を見る
Alcohol flushing reaction (AFR) is known as one of risks for esophageal squamous cell cancer and scientists have been elucidating this issue. However, little attention has been given to relevant imaging features. This study aims to investigate whether physiological F-fluorodeoxyglucose (FDG) uptake patterns in vertebrae are associated with drinking-habit or AFR. Japanese male patients who underwent FDG positron emission tomography/computed tomography for evaluation of their known or suspected malignancy or inflammatory disease were asked about their drinking-habit and AFR. Altogether, 192 patients, 139 everyday-drinkers and 53 non-drinkers were evaluated. Comparing the FDG uptake between in the thoracic region and that in the lumbar region, vertebral uptake was visually classified into 4 patterns: Ld, dominant in lumbar region; TL, almost equal in both regions; BL, slightly higher in thoracic region (borderline pattern); Td, dominant in thoracic region. The uptake patterns were evaluated according to drinking-habit (everyday- or non-drinker), AFR (flusher or non-flusher) and the combination of these two factors (habit/reaction: everyday-drinker/flusher, everyday-drinker/non-flusher, non-drinker/flusher, or non-drinker/non-flusher). There were 95 flushers (51 everyday-drinkers and 44 non-drinkers) and 97 non-flushers (88 everyday-drinkers and 9 non-drinkers). Ld, TL, BL, and Td patterns were observed in 0, 109 (56.8%), 31 (16.1%), and 52 (27.1%) patients, respectively. Td and BL patterns were more frequently observed in everyday-drinkers compared with non-drinkers (p = 0.0467). Though the uptake patterns did not differ between in flushers and non-flushers (p = 0.116), Td pattern was more frequently observed in everyday-drinkers/flusher (51%) compared with everyday-drinkers/non-flusher (20.5%), non-drinker/flusher (13.6%), and non-drinker/non-flusher (22.2%) (p = 0.0014). Td pattern was observed in patients with various diseases, with higher frequency in esophageal cancer, head and neck cancer and lung cancer compared with other diseases. In conclusion, drinking-habit and AFR were related to the vertebral uptake pattern with decreased uptake in the lumbar region in Japanese male patients.