量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum and Radiological Science and Technology.
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The effect of the plateau region carbon ion (C-ion) beams (13 keV/µm) on lipid molecules was investigated by 2,2,6-trimethyl-4-(4-nitrobenzo[1,2,5]oxadiazol-7-ylamino)-6-pentylpiperidine-1-oxyl (NBD-Pen), a highly selective fluorescence probe for lipid radicals with high sensitivity. An increase in the fluorescence intensity due to lipid radical adducts of NBD-Pen was observed for the isopropyl myristate (IPM) and acetonitrile (MeCN) solutions of NBD-Pen after the plateau region C-ion irradiation, while such an increase was not observed for a methanol (MeOH) solution of NBD-Pen. A slight increase in the fluorescence intensity was observed after 30 Gy plateau region C-ion irradiation to phosphate buffer solutions containing unsaturated fatty acids, such as linoleic acid (LA) and alpha-linoleic acid (ALA), and NBD-Pen.
Effect of Plateau Carbon-Ion Beams on Lipid Molecules
