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Micro-Slit X-Ray Irradiation Reveals Testicular Tissue-Sparing Effects: An Attempt at High-Precision Radiotherapy for Male Fertility Preservation
https://repo.qst.go.jp/records/80934
https://repo.qst.go.jp/records/809347919ca5f-ba87-40e3-a2b0-0281b2f84e26
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2020-11-11 | |||||
タイトル | ||||||
タイトル | Micro-Slit X-Ray Irradiation Reveals Testicular Tissue-Sparing Effects: An Attempt at High-Precision Radiotherapy for Male Fertility Preservation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Fukunaga, H.
× Fukunaga, H.× Prise, K.M.× Yokoya, A.× Yokoya, Akinari |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The preservation of male fertility during or after radiotherapy has long been desired to improve the quality of life for cancer survivors during their reproductive years. To approach this clinical issue, we focused on the tissue-sparing effect (TSE) in the testes in response to microbeam radiotherapy (MRT). In this study, we used ex vivo testicular tissue cultures obtained from Acr-GFP transgenic mice and revealed, for the first time, the significant TSE of high-precision MRT for maintaining spermatogenesis using live-tissue fluorescence imaging. This suggests that MRT is a promising approach for preserving male fertility. | |||||
書誌情報 |
Photon Factory Highlights 2019 p. 54-55, 発行日 2020-11 |
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関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www2.kek.jp/imss/pf/science/publ/pfhl/2019/19hl4_7.pdf |