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Magnetometer with nitrogen-vacancy center in a bulk diamond for detecting magnetic nanoparticles in biomedical applications
https://repo.qst.go.jp/records/78542
https://repo.qst.go.jp/records/785429a93bce3-2297-47a6-a717-738b4838d151
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-01-24 | |||||
タイトル | ||||||
タイトル | Magnetometer with nitrogen-vacancy center in a bulk diamond for detecting magnetic nanoparticles in biomedical applications | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kuwahata, Akihiro
× Kuwahata, Akihiro× Kitaizumi, Takahiro× Saichi, Kota× Sato, Takumi× Igarashi, Ryuji× Ohshima, Takeshi× Masuyama, Yuta× Iwasaki, Takayuki× Hatano, Mutsuko× Jelezko, Fedor× Kusakabe, Moriaki× Yatsui, Takashi× Sekino, Masaki× Ryuji, Igarashi× Takeshi, Ohshima× Yuta, Masuyama |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We developed a novel magnetometer that employs negatively charged nitrogen-vacancy (NV–) centers in diamond, to detect the magnetic field generated by magnetic nanoparticles (MNPs) for biomedical applications. The compact probe system is integrated into a fiber-optics platform allowing for a compact design. To detect signals from the MNPs effectively, we demonstrated, for the first time, the application of an alternating current (AC) magnetic field generated by the excitation coil of several hundred microteslas for the magnetization of MNPs in diamond quantum sensing. In the lock-in detection system, the minimum detectable AC magnetic field (at a frequency of 1.025 kHz) was approximately 57.6 nT for one second measurement time. We were able to detect the micromolar concentration of MNPs at distances of a few millimeters. These results indicate that the magnetometer with the NV- centers can detect the tiny amounts of MNPs, thereby offering potential for future biomedical applications. | |||||
書誌情報 |
Scientific Reports 巻 10, p. 2483, 発行日 2020-02 |
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出版者 | ||||||
出版者 | Springer Nature | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2045-2322 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1038/s41598-020-59064-6 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.nature.com/articles/s41598-020-59064-6 |