量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
Thank you very much for using our website. On the 11th of March 2019, this site was moved from our own network server to the JAIRO Cloud network server. If you previously bookmarked this site, that bookmark will no longer work. We would be grateful if you could bookmark the website again. Thank you very much for your understanding and cooperation.
The International School for Advanced Studies (SISSA), find out more SiPM-based dual-ended-readout DOI-TOF PET module based on mean-time method
利用統計を見る
Positron emission tomography (PET) with high resolution and high sensitivity is desirable for detecting cancers and neurological diseases. In this work, a depth-of-interaction (DOI)-time-of-flight (TOF) PET has been attempted to achieve both high spatial and high timing resolution. Dual-ended readout is a simple technique that can provide excellent timing and DOI resolutions and consistent signal arrival times, regardless of the DOI position along the scintillation crystal, as a mean-time method is used. A dual-ended readout DOI-TOF PET module consisting of a 6 × 6 array of 2 × 2 × 20 mm3 saw-cut cerium-doped lutetium-yttrium oxyorthosilicate (LYSO) crystals is constructed. Both ends of the LYSO crystal array are optically coupled to a multi-pixel photon counter (MPPC) with 4 × 4 channels. The sixteen MPPC outputs are reduced to four position signals using a charge division circuit (CDC) board, and the timing signal is extracted from the common cathode of the MPPC. The four position signals from the MPPC are digitized by a DRS4-based high-speed waveform digitizer with a sampling rate of 5 GSa/s. A 22Na source is placed in front of a reference detector and at the side of the dual-ended readout DOI-TOF PET module in five steps of 2 mm, 6 mm, 10 mm, 14 mm, and 18 mm to measure the DOI, coincidence timing resolutions (CTRs), and mean-times. The full-width-half-maximums (FWHMs) of DOI resolutions and CTRs varied from 3.0 mm to 3.8 mm, with an average of 3.5 mm, and from 333 ps to 367 ps, with an average of 349 ps, respectively. The average of the slopes of the mean-time versus DOI position, for the 36 crystals, was −0.60 ± 1.68 ps/nm, which was consistent with the null value. The dual-ended readout DOI-TOF PET module based on the mean-time method produced both good DOI and CTRs, and consistent signal arrival times. The found solution would be the most advantageous in the small aperture PET systems, such as those for brain and breast imaging.
The International School for Advanced Studies (SISSA), find out more SiPM-based dual-ended-readout DOI-TOF PET module based on mean-time method
