量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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We have investigated degeneration of the nerve fibers in chronic cerebral hypoperfusion model mice using DTI. Simple t-tests indicated that there are significant differences in CBF between the control and occluded sides of the brain, but there was no significant difference for MD. However, analysis of covariance showed that MD was strongly correlated with CBF, and that there were significant differences in MD between the contra- and ipsilateral sides. The result suggests degeneration of the nerve fibers due to chronic hypoperfusion. It is also suggested that CBF-related signal changes might be important for pathological diagnosis with DTI.
Relationship between cerebral blood flow and water diffusion in the brain of misery perfusion model mice
