量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果(学会誌発表論文、学会発表、研究開発報告書、特許等)を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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Radiation exposure elevates risk of cancer. Carcinogenesis is a process of forming cancer, which is considered to originate from a cell that harbors an important genetic change (i.e., mutation). There are many knowledge gaps, however, about the mechanism of carcinogenesis induced by radiation. Application of quantum technologies potentially has great impacts in many fields of life science including cancer research and radiation biology. We therefore aim at applying quantum technologies to facilitate research on the mechanism of radiation carcinogenesis. Among a myriad of technologies developed in QST, we put our focus on quantum beam technologies as sources of radiation for induction of cancer-initiating (‘radiation signature’) mutations, infrared laser spectrometry as novel pathological analyses (‘quantum pathology’) of tumor tissues, and two photon imaging for studying the initial stages of cancer induction (‘lineage imaging’ and ‘mutation imaging’). In the presentation, we briefly introduce our current project on radiation carcinogenesis in an animal model of breast cancer and related application of quantum technologies.