量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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Forty-nine patients with Head and Neck tumor were studied using C-11 methionine with combined PET/CT scanner, Siemens Biograph, and precise fusion PET and CT images were acquired. We aligned CT images of PET/CT and MRI acquired on different scanners using a co-registration computer algorithm of Dr,View software on PC machine. And then we swapped CT images with MRI images to get MRI-PET fusion images. Results: Due to the rich anatomical imformation of both CT and MRI images, our computer algorithm, AMIR, resulted in accurate MRI-CT fusion, and then precise MRI-PET fusion was successfully achieved by swapping CT images with MRI images. MRI-PET fusion images rather than PET fusion images showed clearly tumor extent or invasion into surrounding tissue, especially muscles and soft tissues, and it played a significant role in diagnosis, staging and treatment. Conclusions: We could get precisely co-registered MRI and PET images with the help of PET/CT fusion images. MRI-PET fusion images. MRI-PET fusion images were useful especially for diagnosis tumor extent or invasion into muscles and soft tissues in Head and Neck.
頭頚部・脳腫瘍におけるPET-CT-MRI/MRS画像の有用性の検討
