量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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To elucidate molecular mechanisms for the induction of radiation-induced adaptive response through radiation-induced bystander responses, Human non-small lung cancer cells bearing the wild-type p53 were irradiated with heavy ion microbeams in QST-Takasaki. By the analysis of surviving fraction, the phenomenon, “radiation-induced adaptive response” was actually induced in the cells of both 10-cell irradiated and non-irradiated neighboring colonies. The response was almost completely suppressed by the addition of NO scavenger to the medium. Collectively, radiation-induced adaptive response can be induced by radiation-induced, NO-mediated bystander response.
雑誌名
QST Takasaki Annual Report 2015
ページ
116 - 116
発行年
2017-03
出版者
Takasaki Advanced Radiation Research Institute, QST
Analysis of Mechanisms for the Induction of Radiation-Induced Adaptive Response by Bystander Response
