量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum and Radiological Science and Technology.
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To apply diffusion-weighted imaging (DWI) using echo-planar imaging with SENSE (sensitivity encoding) to prostate and evaluate whether prostate carcinoma can be demonstrated.
Two healthy volunteers and 15 patients with histologically proven prostate cancer were examined with 1.5T MR unit. Following routine axial and coronal T2 and axial T1-weighted images, DWI was obtained in the axial plane with a single-shot echo-planar-imaging (EPI) sequence using SENSE method. A b value was 700s/mm2. Diffusion-weighted gradients were applied in 6different directions in each of the measurements. ADC (apparent diffusion coefficient) map and Diffusion tesor imaging (DTI) were calculated with a computer program on numerical integration software. Vector-icon image were obtained to visualize the diffusion anisotropy of the prostate.
With ADC map, the lesion of prostate carcinoma was demonstrated as low intensity area and ADC map helped the localization of carcinoma. With DTI, a concentric anisotrophy was demonstrated in the normal prostate gland. The lesion of carcinoma deranged that anisotrophy. In two patient, low intensity area in ADC map was disappeared after HIMAC treatment. The ADC map and DTI have a potential to reveal prostate carcinoma and can be used for the evaluattion of the treatment.
前立腺癌の高速撮影法SENSE(sensitivity encoding)を用いた拡散強調画像
