WEKO3
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Low-dose radiation-induced risk in spermatogenesis
https://repo.qst.go.jp/records/48474
https://repo.qst.go.jp/records/484742225223c-d56b-440f-bab7-c6141721a95c
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-02-07 | |||||
タイトル | ||||||
タイトル | Low-dose radiation-induced risk in spermatogenesis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Fukunaga, Hisanori
× Fukunaga, Hisanori× T., Butterworth Karl× Yokoya, Akinari× Ogawa, Takehiko× M., Prise Kevin× 横谷 明徳 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To discuss low-dose radiation-induced risks to male fertility focusing on potential mechanisms of low-dose radiation-induced damage on spermatogenesis, epidemiological studies of environmental radiation effects on sperm parameters and transgenerational effects following exposure of spermatogonial stem cells (SSCs). Spermatogenesis produces mature male gametes, spermatozoa, which fertilize their counterpart female gametes, oocytes. The robust maintenance system of spermatogenesis is essential for genomic conservation, however, male fertility can be readily impacted by exposure to environmental, chemical and physical factors including ionizing radiation. The mammalian testes are known to be radiosensitive yet the underlying molecular mechanisms of lowdose radiation-induced risks for spermatogenesis remain unclear. Furthermore, evidence characterising transgenerational effects following exposure of SSCs remain controversial. Current concerns over the possible effects of low-dose radiation exposure on spermatogenesis requires further elucidation that may be resolved comparing and integrating observed experimental and epidemiological data. |
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書誌情報 |
International Journal of Radiation Biology 巻 93, 号 12, p. 1291-1298, 発行日 2017-08 |
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出版者 | ||||||
出版者 | Taylor&Francis | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1080/09553002.2017.1355579 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.tandfonline.com/doi/full/10.1080/09553002.2017.1355579 | |||||
関連名称 | http://www.tandfonline.com/doi/full/10.1080/09553002.2017.1355579 |