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Radiation dose was calculated by radiation planning. Irradiated BM was divided into three groups (\u003c10% of maximum dose, 10-30%, and \u003e30%). \nResults \n18FLT uptake clearly decreased at \u003e10% irradiated areas and mildly decreased at \u003c10% areas. 18FLT uptake was lowest just after CIRT, somewhat increased at 3 months, and remained unchanged for more than 1 year. There was no significant difference between 10-30% and \u003e30% areas. \nConclusion \n18FLT revealed that BM function decreased by small dose such as \u003c4.2-4.4 GyE/1 fraction of CIRT and is eradicated by \u003e4.2-4.4 GyE/1 fraction.", "subitem_description_type": "Abstract"}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/s11307-010-0363-4", "subitem_relation_type_select": "DOI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1536-1632", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Koizumi, Mitsuru"}], "nameIdentifiers": [{"nameIdentifier": "458399", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saga, Tsuneo"}], "nameIdentifiers": [{"nameIdentifier": "458400", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Inubushi, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "458401", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fukumura, Toshimitsu"}], "nameIdentifiers": [{"nameIdentifier": "458402", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshikawa, Kyosan"}], "nameIdentifiers": [{"nameIdentifier": "458403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Naoyoshi"}], "nameIdentifiers": [{"nameIdentifier": "458404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakajima, Mio"}], "nameIdentifiers": [{"nameIdentifier": "458405", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugane, Toshio"}], "nameIdentifiers": [{"nameIdentifier": "458406", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Baba, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "458407", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小泉 満", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458408", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐賀 恒夫", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458409", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "犬伏 正幸", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458410", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "福村 利光", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458411", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "吉川 京燦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458412", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "山本 直敬", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458413", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "中嶋 美緒", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458414", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "須金 紀雄", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458415", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "馬場 雅行", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "458416", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Uptake Decrease of Proliferative PET Tracer 18FLT in Bone Marrow after Carbon Ion Therapy in Lung Cancer", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Uptake Decrease of Proliferative PET Tracer 18FLT in Bone Marrow after Carbon Ion Therapy in Lung Cancer"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/46053", "pubdate": {"attribute_name": "公開日", "attribute_value": "2011-05-23"}, "publish_date": "2011-05-23", "publish_status": "0", "recid": "46053", "relation": {}, "relation_version_is_last": true, "title": ["Uptake Decrease of Proliferative PET Tracer 18FLT in Bone Marrow after Carbon Ion Therapy in Lung Cancer"], "weko_shared_id": -1}
Uptake Decrease of Proliferative PET Tracer 18FLT in Bone Marrow after Carbon Ion Therapy in Lung Cancer
https://repo.qst.go.jp/records/46053
https://repo.qst.go.jp/records/4605300a6f051-3a57-4711-af75-4bd8784da899
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-05-23 | |||||
タイトル | ||||||
タイトル | Uptake Decrease of Proliferative PET Tracer 18FLT in Bone Marrow after Carbon Ion Therapy in Lung Cancer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Koizumi, Mitsuru
× Koizumi, Mitsuru× Saga, Tsuneo× Inubushi, Masayuki× Fukumura, Toshimitsu× Yoshikawa, Kyosan× Yamamoto, Naoyoshi× Nakajima, Mio× Sugane, Toshio× Baba, Masayuki× 小泉 満× 佐賀 恒夫× 犬伏 正幸× 福村 利光× 吉川 京燦× 山本 直敬× 中嶋 美緒× 須金 紀雄× 馬場 雅行 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose The aim of this study was to investigate the change of 3'-[18F]fluoro-3'-deoxy-l-thymidine (18FLT) uptake in normal bone marrow (BM) after inevitable radiation. Procedures Twenty-one non-small cell lung cancer patients who received carbon ion radiotherapy (CIRT) were studied with 18FLT-positron emission tomography/computed tomography (PET/CT) at pre- and post-CIRT. Radiation dose was calculated by radiation planning. Irradiated BM was divided into three groups (<10% of maximum dose, 10-30%, and >30%). Results 18FLT uptake clearly decreased at >10% irradiated areas and mildly decreased at <10% areas. 18FLT uptake was lowest just after CIRT, somewhat increased at 3 months, and remained unchanged for more than 1 year. There was no significant difference between 10-30% and >30% areas. Conclusion 18FLT revealed that BM function decreased by small dose such as <4.2-4.4 GyE/1 fraction of CIRT and is eradicated by >4.2-4.4 GyE/1 fraction. |
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書誌情報 |
Molecular Imaging and Biology 巻 13, 号 3, p. 577-582, 発行日 2010-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1536-1632 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s11307-010-0363-4 |