WEKO3
アイテム
{"_buckets": {"deposit": "26e419a5-bcbd-4bff-8f29-2453819538f5"}, "_deposit": {"created_by": 1, "id": "45764", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "45764"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00045764", "sets": ["1"]}, "author_link": ["454946", "454956", "454940", "454947", "454949", "454951", "454950", "454937", "454941", "454942", "454953", "454936", "454943", "454939", "454952", "454948", "454934", "454932", "454945", "454955", "454931", "454935", "454954", "454933", "454938", "454944"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "3047", "bibliographicPageStart": "3043", "bibliographicVolumeNumber": "30", "bibliographic_titles": [{"bibliographic_title": "The Journal of Neuroscience"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Several animal studies have demonstrated functional roles of dopamine (DA) D1 and D2 receptors in amygdala activity. However, the\ncontribution of DA D1 and D2 receptors to amygdala response induced by affective stimuli in human is unknown. To investigate the\ncontribution of DA receptor subtypes to amygdala reactivity in human, we conducted a multimodal in vivo neuroimaging study in which\nDA D1 and D2 receptor bindings in the amygdala were measured with positron emission tomography (PET), and amygdala response\ninduced by fearful faces was assessed by functional magnetic resonance imaging (fMRI) in healthy volunteers. We used multimodality\nvoxelwise correlation analysis between fMRI signal and DA receptor binding measured by PET. DA D1 binding in the amygdala was\npositively correlated with amygdala signal change in response to fearful faces, but DA D2 binding in the amygdala was not related to\namygdala signal change. DA D1 receptors might play a major role in enhancing amygdala response when sensory inputs are affective.", "subitem_description_type": "Abstract"}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0270-6474", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takahashi, Hidehiko"}], "nameIdentifiers": [{"nameIdentifier": "454931", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takano, Harumasa"}], "nameIdentifiers": [{"nameIdentifier": "454932", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kodaka, Fumitoshi"}], "nameIdentifiers": [{"nameIdentifier": "454933", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Arakawa, Ryosuke"}], "nameIdentifiers": [{"nameIdentifier": "454934", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamada, Makiko"}], "nameIdentifiers": [{"nameIdentifier": "454935", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Otsuka, Tatsui"}], "nameIdentifiers": [{"nameIdentifier": "454936", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hirano, Yoshiyuki"}], "nameIdentifiers": [{"nameIdentifier": "454937", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kikyo, Hideyuki"}], "nameIdentifiers": [{"nameIdentifier": "454938", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okubo, Yoshiro"}], "nameIdentifiers": [{"nameIdentifier": "454939", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kato, Motoichiro"}], "nameIdentifiers": [{"nameIdentifier": "454940", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Obata, Takayuki"}], "nameIdentifiers": [{"nameIdentifier": "454941", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "454942", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suhara, Tetsuya"}], "nameIdentifiers": [{"nameIdentifier": "454943", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "高橋 英彦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454944", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "高野 晴成", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454945", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小高 文聰", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454946", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "荒川 亮介", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454947", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "山田 真希子", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454948", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "大塚 達以", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454949", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "平野 好幸", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454950", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "桔梗 英幸", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454951", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "大久保 善朗", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454952", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "加藤 元一郎", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454953", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小畠 隆行", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454954", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "伊藤 浩", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454955", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "須原 哲也", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "454956", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Contribution of dopamine D1 and D2 receptors to amygdala activity in human", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Contribution of dopamine D1 and D2 receptors to amygdala activity in human"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/45764", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-03-09"}, "publish_date": "2010-03-09", "publish_status": "0", "recid": "45764", "relation": {}, "relation_version_is_last": true, "title": ["Contribution of dopamine D1 and D2 receptors to amygdala activity in human"], "weko_shared_id": -1}
Contribution of dopamine D1 and D2 receptors to amygdala activity in human
https://repo.qst.go.jp/records/45764
https://repo.qst.go.jp/records/45764f94b98b5-4ecd-4919-8dd6-9d400960c1e8
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2010-03-09 | |||||
タイトル | ||||||
タイトル | Contribution of dopamine D1 and D2 receptors to amygdala activity in human | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Takahashi, Hidehiko
× Takahashi, Hidehiko× Takano, Harumasa× Kodaka, Fumitoshi× Arakawa, Ryosuke× Yamada, Makiko× Otsuka, Tatsui× Hirano, Yoshiyuki× Kikyo, Hideyuki× Okubo, Yoshiro× Kato, Motoichiro× Obata, Takayuki× Ito, Hiroshi× Suhara, Tetsuya× 高橋 英彦× 高野 晴成× 小高 文聰× 荒川 亮介× 山田 真希子× 大塚 達以× 平野 好幸× 桔梗 英幸× 大久保 善朗× 加藤 元一郎× 小畠 隆行× 伊藤 浩× 須原 哲也 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Several animal studies have demonstrated functional roles of dopamine (DA) D1 and D2 receptors in amygdala activity. However, the contribution of DA D1 and D2 receptors to amygdala response induced by affective stimuli in human is unknown. To investigate the contribution of DA receptor subtypes to amygdala reactivity in human, we conducted a multimodal in vivo neuroimaging study in which DA D1 and D2 receptor bindings in the amygdala were measured with positron emission tomography (PET), and amygdala response induced by fearful faces was assessed by functional magnetic resonance imaging (fMRI) in healthy volunteers. We used multimodality voxelwise correlation analysis between fMRI signal and DA receptor binding measured by PET. DA D1 binding in the amygdala was positively correlated with amygdala signal change in response to fearful faces, but DA D2 binding in the amygdala was not related to amygdala signal change. DA D1 receptors might play a major role in enhancing amygdala response when sensory inputs are affective. |
|||||
書誌情報 |
The Journal of Neuroscience 巻 30, 号 8, p. 3043-3047, 発行日 2010-02 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0270-6474 |