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Carbon Ion Radiotherapy for Skull Base Chordoma
https://repo.qst.go.jp/records/45557
https://repo.qst.go.jp/records/45557dc5493e9-b5b6-41cf-804c-769001c39fae
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-06-26 | |||||
タイトル | ||||||
タイトル | Carbon Ion Radiotherapy for Skull Base Chordoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Mizoe, Junetsu
× Mizoe, Junetsu× Hasegawa, Azusa× Takagi, Ryo× Bessho, Hiroki× Onda, Takeshi× Tsujii, Hirohiko× 溝江 純悦× 長谷川 安都佐× 高木 亮× 別所 央城× 恩田 健志× 辻井 博彦 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: To present the results of the clinical study of carbon ion radiotherapy (CIRT) for skull base and paracervical spine tumors at the National Institute of Radiological Sciences in Chiba, Japan. Methods: The study is comprised of three protocols: a pilot study, a phase I/II dose escalation study, and a phase II study. All the patients were treated by 16 fractions for 4 weeks with total doses of 48.0, 52.8, 57.6, and 60.8 Gy equivalents (GyE). Results: As a result of the dose escalation study of CIRT for skull base tumors, a dose fractionation of 60.8 GyE/16 fractions for 4 weeks was decided as the recommended dose because of acceptable normal tissue reactions and good local tumor control. Conclusions: Preliminary results of the phase II clinical study of CIRT for skull base chordoma showed local control at 5 years at 100%, and normal tissues showed a mild reaction without any severe morbidity of important organs. | |||||
書誌情報 |
Skull Base : An Interdisciplinary Approach 巻 19, 号 3, p. 219-224, 発行日 2009-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1531-5010 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1055/s-0028-1114295 |