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Mycophenolic acid as a latent agonist of PPAR gamma
https://repo.qst.go.jp/records/44957
https://repo.qst.go.jp/records/44957e03caa3d-6b9a-4a66-a940-a2c780d74e4c
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-08-28 | |||||
タイトル | ||||||
タイトル | Mycophenolic acid as a latent agonist of PPAR gamma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ubukata, Makoto
× Ubukata, Makoto× Taki, Keiko× et.al× 瀧 景子 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Mycophenolic acid (MPA), known as an inhibitor of inosine monophosphate dehydrogenase (IMPDH), was found to inhibit the differentiation of 3T3-L1 pre-adipocytes into mature adipocytes. Although the effect of MPA was attributed to inhibition of IMPDH, we uncovered a hidden biological property of MPA as an agonist of peroxisome proliferator activated receptor gamma (PPAR gamma). | |||||
書誌情報 |
Bioorganic & Medicinal Chemistry Letters 巻 17, 号 17, p. 4767-4770, 発行日 2007-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0960-894X | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.bmcl.2007.06.059 |